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Cell line nameBICR 18
Accession numberICLC HTL10003
Brief descriptionSpecies: human; Tissue: larynx; Tumor: carcinoma, squamous cell
DescriptionSpecies: human male; Tissue: larynx; Tumor: carcinoma, squamous cell; Derived from: lymph node metastasis
DepositorDr U. Pfeffer, Molecular Biology Dept, IST at ABC, Genoa, Italy
Reference paperUnknown
Morphology and growthcontinuous culture, grown as monolayer, morphology epithelial
Culture conditionsDMEM + 10% FBS + 2mM L-Glutamine; Split 1:3-1:6 using trypsin/EDTA, 37C, 5% CO2
DistributionCell line available for distribution. For non-commercial investigative use only.
Hazard
Tumorigenicitytumorigenic in athymic mice
Freezing medium95% FCS + 5% DMSO
Validation assaysIdentification confirmed by Short Tandem Repeat (STR) profile.
Further bibliographyCancer Res. 1999; 59(11):2516-21 - PMID: 10363964
Mol Carcinog. 1995; 13(4):254-65. - PMID: 7646764
Oncogene 1997;14(16):1955-64 - PMID: 9150362
Commentsknown mutation:p53, p16 and p14ARF.

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